How Do You Spell MYOTONIA NEONATORUM?

1. Myotonia neonatorum is a medical condition characterized by muscular stiffness or prolonged muscle contractions that occur in newborn infants shortly after birth. It is a rare genetic disorder inherited in an autosomal dominant manner, although sporadic cases can also occur.

   The main presenting feature of myotonia neonatorum is the delayed relaxation of skeletal muscles after voluntary or involuntary contraction. This results in a stiff and rigid appearance of the affected muscles and may cause difficulty in movement, particularly in regards to initiating or ending a muscle contraction. These episodes of muscle stiffness are typically more pronounced during periods of rest or inactivity, and they tend to improve with repeated movement.

   The stiffness experienced in myotonia neonatorum is caused by an abnormality in the functioning of the muscle fibers. Specifically, there is an alteration in the movement of important chemical ions, such as sodium and chloride, in and out of the muscle cells. This leads to an electrical imbalance within the muscle fibers, affecting their ability to relax efficiently.

   Although myotonia neonatorum is generally a benign condition, it can cause significant distress for the affected infant and their caretakers. The stiffness and rigidity of the muscles can interfere with feeding, breathing, and overall physical development. However, with appropriate supportive care and management, the prognosis for affected individuals is generally good.

   To diagnose myotonia neonatorum, the physician may perform a thorough physical examination, evaluate the patient's medical history, and may conduct relevant genetic testing to confirm the diagnosis. Treatment options mainly involve supportive measures, which may include physical therapy and muscle relaxant medications to alleviate muscle stiffness and improve mobility. With early recognition and appropriate management, individuals with myotonia neonatorum can lead a relatively normal and healthy life.

2. Tetanism.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for MYOTONIA NEONATORUM

The word "myotonia neonatorum" was derived from two different terms:

1. Myotonia: The term "myotonia" originates from the Greek words "myo" meaning "muscle" and "tonos" meaning "tension" or "tone". Therefore, myotonia refers to the condition characterized by the prolonged contraction or stiffening of muscles after voluntary contraction or mechanical stimulation.

2. Neonatorum: The term "neonatorum" is derived from the Latin word "neonatus", which means "newborn". It is a genitive form that indicates the condition is specifically related to newborns or infants.