MANNOSEPHOSPHATE ISOMERASE Meaning and
Definition
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Mannosephosphate isomerase is an enzyme that plays a crucial role in the metabolic pathway of carbohydrate metabolism. It is responsible for catalyzing the interconversion of mannose-6-phosphate (M6P) and fructose-6-phosphate (F6P).
Specifically, mannosephosphate isomerase facilitates the reversible isomerization of M6P to F6P through an intramolecular rearrangement reaction. This enzymatic process involves the movement of the hydroxyl group at the C1 position of the sugar molecule, resulting in the conversion of the aldose form (M6P) to the ketose form (F6P), or vice versa.
The significance of mannosephosphate isomerase lies in its role as a key regulator of carbohydrate metabolism and its involvement in various biochemical pathways. It contributes to the synthesis of important biomolecules such as glycogen, glucose, and nucleotide sugars. Additionally, mannosephosphate isomerase is vital for the production of mannose, an essential sugar used for glycosylation in the biosynthesis of glycoproteins and glycolipids.
Deficiencies or dysfunctions in mannosephosphate isomerase activity can lead to metabolic disorders such as carbohydrate metabolism disorders or hereditary fructose intolerance. Therefore, understanding the structure, function, and regulation of mannosephosphate isomerase is crucial for both basic scientific research and biomedical applications.
Common Misspellings for MANNOSEPHOSPHATE ISOMERASE
- nannosephosphate isomerase
- kannosephosphate isomerase
- jannosephosphate isomerase
- mznnosephosphate isomerase
- msnnosephosphate isomerase
- mwnnosephosphate isomerase
- mqnnosephosphate isomerase
- mabnosephosphate isomerase
- mamnosephosphate isomerase
- majnosephosphate isomerase
- mahnosephosphate isomerase
- manbosephosphate isomerase
- manmosephosphate isomerase
- manjosephosphate isomerase
- manhosephosphate isomerase
- mannisephosphate isomerase
- mannksephosphate isomerase
- mannlsephosphate isomerase
- mannpsephosphate isomerase
- mann0sephosphate isomerase
Etymology of MANNOSEPHOSPHATE ISOMERASE
The word "Mannosephosphate Isomerase" can be broken down into two parts: "mannosephosphate" and "isomerase".
The term "mannosephosphate" is derived from the words "mannose" and "phosphate". Mannose is a sugar found in various food sources and is an important component in the biosynthesis of various carbohydrates. It is derived from the German word "Mannose", which was coined by German chemist Emil Fischer in 1888. The word "phosphate" refers to a chemical compound that contains the element phosphorus and is crucial in various biological processes.
The word "isomerase" is a combination of the prefix "iso-" and the word "merase". "Iso-" means equal or similar, while the term "-merase" is derived from the Greek word "meros", meaning "part" or "unit".
