CALCEINAM:
Calceinam is a fluorescent calcium indicator dye that is widely used in various biological and medical research applications. It is a derivative of calcein, a calcium chelator, which means it has the ability to bind to calcium ions and exhibit fluorescence upon calcium binding.
Calceinam is typically used to measure changes in intracellular calcium concentrations in living cells. It is often utilized in fluorescent microscopy and flow cytometry techniques to visualize and quantify calcium fluctuations within cells. The fluorescence emitted by calceinam increases as calcium levels rise, allowing researchers to monitor changes in calcium signaling pathways and cellular response to various stimuli.
Due to its green fluorescence emission, calceinam is commonly combined with red fluorescent dyes to simultaneously analyze multiple cellular processes. This enables investigators to study calcium dynamics along with other parameters such as membrane potentials, reactive oxygen species, or pH changes.
Additionally, calceinam is employed in studying a wide range of biological processes, including cell proliferation, apoptosis, neurotransmission, muscle contraction, and immune cell activation. Its versatility and ease of use have made it an important tool in understanding cellular physiology and pathology.
In summary, calceinam is a fluorescent calcium indicator dye that permits real-time monitoring of intracellular calcium levels in living cells. It facilitates the investigation of various cellular processes, making it an indispensable agent in biological and medical research.
